3′,4′-Didehydro-3′-deoxythymidine triphosphate – CAS 2499590-45-1

3′,4′-Didehydro-3′-deoxythymidine triphosphate – CAS 2499590-45-1

€1700 – €3000

3′,4′-Didehydro-3′-deoxythymidine triphosphate – CAS 2499590-45-1 is synthesized by Santiago Lab (Prague, Czech Republic). 

Purity (LC-MS)

min 95%

Package contents

3′,4′-Didehydro-3′-deoxythymidine triphosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.
SizeAvailabilityPriceQuantity
1 mg

In stock

 €1700
5 mg

In stock

 €3000

3′,4′-Didehydro-3′-deoxythymidine triphosphate – CAS 2499590-45-1

Characterisation

CAS: 2499590-45-1

IUPAC Name: ((R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4,5-dihydrofuran-2-yl)methyl tetrahydrogen triphosphate

Other names: DdhT-TP, Ddh-T-TP,

Molecular weight: 464.15 g/mol

Molecular formula: C10H15N2O13P3

InChI: InChI=1S/C10H15N2O13P3/c1-6-4-12(10(14)11-9(6)13)8-3-2-7(23-8)5-22-27(18,19)25-28(20,21)24-26(15,16)17/h2,4,8H,3,5H2,1H3,(H,18,19)(H,20,21)(H,11,13,14)(H2,15,16,17)/t8-/m1/s1

Description

3′,4′-Didehydro-3′-deoxythymidine triphosphate is a metabolite of 3′,4′-Didehydro-3′-deoxythymidine (DdhT). A related compound,  3′,4′-didehydro-3′-deoxycytidine triphosphate has been proven to have antiviral properties. It has the ability to prevent the replication of several viruses, including the Zika virus. This molecule is naturally produced in mammals through the dehydration of cytidine triphosphate (CTP), which is catalyzed by the enzyme viperin.

References

  • WO2020202142 A2 2020-10-08

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