3′,4′-Didehydro-3′-deoxythymidine monophosphate

3′,4′-Didehydro-3′-deoxythymidinemonophosphate

€1300 – €2800

3′,4′-Didehydro-3′-deoxythymidine monophosphate  is synthesized by Santiago Lab (Prague, Czech Republic). 

Purity (LC-MS)

min 95%

Package contents

3′,4′-Didehydro-3′-deoxythymidine monophosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.
SizeAvailabilityPriceQuantity
1 mg

In stock

 €1300
5 mg

In stock

 €2800

3′,4′-Didehydro-3′-deoxythymidine monophosphate

Characterisation

CAS: N.A.

IUPAC Name: ((R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4,5-dihydrofuran-2-yl)methyl dihydrogen phosphate

Other names: DdhT-MP, Ddh-T-MP,

Molecular weight: 304.19 g/mol

Molecular formula: C10H13N2O7P

InChI: InChI=1S/C10H13N2O7P/c1-6-4-12(10(14)11-9(6)13)8-3-2-7(19-8)5-18-20(15,16)17/h2,4,8H,3,5H2,1H3,(H,11,13,14)(H2,15,16,17)/t8-/m1/s1

Description

3′,4′-Didehydro-3′-deoxythymidine monophosphate is a metabolite of 3′,4′-Didehydro-3′-deoxythymidine (DdhT). A related compound,  3′,4′-didehydro-3′-deoxycytidine triphosphate has been proven to have antiviral properties. It has the ability to prevent the replication of several viruses, including the Zika virus. This molecule is naturally produced in mammals through the dehydration of cytidine triphosphate (CTP), which is catalyzed by the enzyme viperin.

References

  • WO2020202142 A2 2020-10-08

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