3′,4′-Didehydro-3′-deoxyadenosine triphosphate– CAS 2761971-65-5

31005800

3′,4′-Didehydro-3′-deoxyadenosine triphosphate– CAS 2761971-65-5 is synthesized by Santiago Lab (Prague, Czech Republic)

Purity (LC-MS)

min 95%

Package contents

3′,4′-Didehydro-3′-deoxyadenosine triphosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.
SizeAvailabilityPriceQuantity
1 mg

In stock

3100
5 mg

In stock

5800

3′,4′-Didehydro-3′-deoxyadenosine triphosphate– CAS 2761971-65-5

Characterisation

CAS: 2761971-65-5

IUPAC Name: ((4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-4,5-dihydrofuran-2-yl)methyl tetrahydrogen triphosphate

Other names: DdhA-TP, Ddh-A-TP, 3′,4′-Didehydro-3′-deoxyadenosine triphosphate, DdhA triphosphate

Molecular weight: 489.17 g/mol

Molecular formula: C10H14N5O12P3

InChI: InChI=1S/C10H14N5O12P3/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(16)1-5(25-10)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h1,3-4,6,10,16H,2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19)/t6-,10+/m0/s1

Description

3′,4′-Didehydro-3′-deoxyadenosine triphosphate is a metabolite of is 3′,4′-Didehydro-3′-deoxyadenosine (DdhA). A related compound,  3′,4′-didehydro-3′-deoxycytidine triphosphate has been proven to have antiviral properties. It has the ability to prevent the replication of several viruses, including the Zika virus. This molecule is naturally produced in mammals through the dehydration of cytidine triphosphate (CTP), which is catalyzed by the enzyme viperin.

 

References

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