3′,4′-Didehydro-3′-deoxythymidine diphosphate

3′,4′-Didehydro-3′-deoxythymidinediphosphate

€2000 – €5000

3′,4′-Didehydro-3′-deoxythymidine diphosphate  is synthesized by Santiago Lab (Prague, Czech Republic). 

Purity (LC-MS)

min 95%

Package contents

3′,4′-Didehydro-3′-deoxythymidine diphosphate triethylammonium salt

This compound is for research use only. We do not sell to patients.
SizeAvailabilityPriceQuantity
1 mg

In stock

 €2000
5 mg

In stock

 €5000

3′,4′-Didehydro-3′-deoxythymidine diphosphate

Characterisation

CAS: N.A.

IUPAC Name: ((R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4,5-dihydrofuran-2-yl)methyl trihydrogen diphosphate

Other names: DdhT-DP, Ddh-T-DP,

Molecular weight: 384.17 g/mol

Molecular formula: C10H14N2O10P2

InChI: InChI=1S/C10H14N2O10P2/c1-6-4-12(10(14)11-9(6)13)8-3-2-7(21-8)5-20-24(18,19)22-23(15,16)17/h2,4,8H,3,5H2,1H3,(H,18,19)(H,11,13,14)(H2,15,16,17)/t8-/m1/s1

Description

3′,4′-Didehydro-3′-deoxythymidine diphosphate is a metabolite of 3′,4′-Didehydro-3′-deoxythymidine (DdhT). A related compound,  3′,4′-didehydro-3′-deoxycytidine triphosphate has been proven to have antiviral properties. It has the ability to prevent the replication of several viruses, including the Zika virus. This molecule is naturally produced in mammals through the dehydration of cytidine triphosphate (CTP), which is catalyzed by the enzyme viperin.

References

  • WO2020202142 A2 2020-10-08

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