7-(Ferrocene-1-yl-ethynyl)-7-deaza-2′-deoxyadenosine triphosphate CAS 1007229-83-5
Characterisation
CAS: 1007229-83-5
IUPAC Name: [2-[4-Amino-7-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-erythro-pentofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]ethynyl]ferrocene
Molecular weight: 698.2 g/mol; 764.2 (Na+ salt)
Molecular formula: C23H25FeN4O12P3
Storage: -20 °C, protect from light
Description
7-(Ferrocene-1-yl-ethynyl)-7-deaza-2′-deoxyadenosine triphosphate is a ferrocene-labeled analog of natural adenosine triphosphate. Ferrocene is used as the gold standard for electrochemical labeling. Its conjugation at 7- position of 7-deaza-2′-deoxyadenosine triphosphate allows enzymatic incorporation of such adenosine triphosphate analog in primer extension reactions and PCR. The compound might be used for electrochemical redox labeling of DNA, site-specific redox labeling or in the development of highly sensitive genosensors.
The product was synthesized and licensed at the IOCB Prague, lab of prof. Michal Hocek.
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