BDP FL NHS ester – CAS 146616-66-2
Characterisation
CAS: 146616-66-2
IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)propanoate
Other names: BDP FL NHS ester
Molecular weight: 389.2 g/mol
Molecular formula: C18H18BF2N3O4
InChI: InChI=1S/C18H18BF2N3O4/c1-11-9-12(2)22-15(11)10-14-4-3-13(23(14)19(22,20)21)5-8-18(27)28-24-16(25)6-7-17(24)26/h3-4,9-10H,5-8H2,1-2H3
Solubility: Good in organic solvents (DMF, DMSO, dichloromethane), limited in water
Excitation/absorption maximum: 503 nm
Emission maximum: 509 nm
Description
Introducing BDP FL NHS ester, an advanced fluorescent dye designed for the 488 nm channel, serving as a superior alternative to fluorescein. Specifically crafted as an amino-reactive dye, it excels in labeling proteins and peptides.
With absorbance and emission spectra aligned with FAM excitation and emission channels, BDP FL NHS ester not only ensures enhanced photostability but also delivers exceptional brightness. Its fluorescence spectrum, narrower than that of FAM, offers superior brightness for monochromator-based instruments, allowing precise tuning of emission wavelength to the dye’s maximum.
This neutral dye boasts a low molecular weight and maintains a high quantum yield in conjugates. A versatile replacement, BDP FL NHS ester outperforms fluorescein (FAM), DyLight™ 488, Cy2™, and other 488 nm dyes with its unique combination of properties. Elevate your research with the unmatched qualities of BDP FL NHS ester.
References
- Tian, J., Zhang, Y., Du, L. et al. Tailored self-assembled photocatalytic nanofibres for visible-light-driven hydrogen production. Nat. Chem. 12, 1150–1156 (2020). https://doi.org/10.1038/s41557-020-00580-3
You can find more fluorescent labels in our catalog: https://www.santiago-lab.com/cat/labels/
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