Entecavir - CAS 142217-69-4

Entecavir – CAS 142217-69-4

€250 – €400

Entecavir – CAS 142217-69-4 is synthesized by Santiago Lab (Prague, Czech Republic). 

Purity (LC-MS)

min 95%

Package contents

Entecavir

This compound is for research use only. We do not sell to patients.
SizeAvailabilityPriceQuantity
50 mg

In stock

 €250
100 mg

In stock

 €400

Entecavir – CAS 142217-69-4

Characterisation

CAS: 142217-69-4

IUPAC Name: 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1H-purin-6-one

Other names: Baraclude, BMS 200475

Molecular weight: 277.28 g/mol

Molecular formula: C12H15N5O3

InChI: InChI=1S/C12H15N5O3/c1-5-6(3-18)8(19)2-7(5)17-4-14-9-10(17)15-12(13)16-11(9)20/h4,6-8,18-19H,1-3H2,(H3,13,15,16,20)/t6-,7-,8-/m0/s1

Description

Entecavir is a potent and selective hepatitis B virus reverse transcriptase inhibitor (EC50 = 3 nM); guanine analog. Inhibits hepatitis B virus replication in HepG2.2.15 cells. Displays selectively over HCMV, HSV-1, VZV, HIV and influenza (EC50 values are 15, 32, 30-60, >10 and >80 μM respectively). Orally bioavailable.

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