HCV-IN-31 – CAS 1998705-62-6
Characterisation
CAS: 1998705-62-6
IUPAC Name: (2R,3R,4R,5R)-5-[2-amino-6-(methylamino)purin-9-yl]-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-ol
Other names: GLXC-25726, HY-138305
Molecular weight: 312.30 g/mol
Molecular formula: C12H17FN6O3
InChI: InChI=1S/C12H17FN6O3/c1-12(13)7(21)5(3-20)22-10(12)19-4-16-6-8(15-2)17-11(14)18-9(6)19/h4-5,7,10,20-21H,3H2,1-2H3,(H3,14,15,17,18)/t5-,7-,10-,12-/m1/s1
Description
HCV-IN-31 is an HCV inhibitor, with an EC50/EC95 of 15.7 μM for HCV replicon. It is a parent nucleoside of the drug Bemnifosbuvir.
References
- https://doi.org/10.1371/journal.pone.0227104
- WO2019200005 A1 2019-10-17
- WO2018048937 A1 2018-03-15
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