N4-Hydroxycytidine – CAS 3258-02-4

N4-Hydroxycytidine – CAS 3258-02-4

€250 – €850

N4-Hydroxycytidine is synthesised by Santiago Lab (Prague, Czech Republic). All products are lyophilized and can easily sustain the shipment oversee.

Purity (LC-MS)

97%+ 

Package contents

N4-Hydroxycytidine

This compound is for research use only. We do not sell to patients.

 

 

 

 

SizeAvailabilityPriceQuantity
1 g

In stock

 €850
100 mg

In stock

 €250

N4-Hydroxycytidine – CAS 3258-02-4

Characterisation

CAS: 3258-02-4

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-(hydroxyamino)pyrimidin-2(1H)-one

Other names: EIDD-1931,  NHC, β-D-N4-hydroxycytidine

Molecular weight: 259.22 g/mol, 

Molecular formula: C9H13N3O6 

InChI: InChI=1S/C9H13N3O6/c13-3-4-6(14)7(15)8(18-4)12-2-1-5(11-17)10-9(12)16/h1-2,4,6-8,13-15,17H,3H2,(H,10,11,16)/t4-,6-,7-,8-/m1/s1

Description

EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV). Molnupiravir is a prodrug of this nucleoside.

References

Chemicals are distributed worldwide

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References

References
1. Kawamoto, A; Kodama, E; Sarafianos, SG; Sakagami, Y; Kohgo, S; Kitano, K; Ashida, N; Iwai, Y; Hayakawa, H; Nakata, H; Mitsuya, H; Arnold, E; Matsuoka, M (2008). "2'-deoxy-4'-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants". The International Journal of Biochemistry & Cell Biology. 40 (11): 2410–20. doi:10.1016/j.biocel.2008.04.007. PMID 18487070.
2. Roy M. Gulick (2018). "Investigational Antiretroviral Drugs: What is Coming Down the Pipeline". Top Antivir Med. 25 (4): 127–132. PMC 5935216. PMID 29689540.

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