Undecynyl-dUTP, CAS 2229952-07-0

Undecynyl-dUTP, CAS 2229952-07-0

€1200 – €3000

Undecynyl-dUTP, CAS 2229952-07-0 is synthesized by Santiago Lab (Prague, Czech Republic). 

Purity (LC-MS)

min 95%

Package contents

Undecynyl-dUTP triethylammonium salt

This compound is for research use only. We do not sell to patients.
SizeAvailabilityPriceQuantity
1 mg

In stock

 €1200
5 mg

In stock

 €3000

Undecynyl-dUTP, CAS 2229952-07-0

Characterisation

CAS: 2229952-07-0

IUPAC Name: α-(undec-10-yn-1-yloxy)thymidine-5’-O-triphosphate triethylamine salt

Other names: Undecynyl-dUTP

Molecular weight: 952.10 g/mol

Molecular formula: C21H35N2O15P3*3C6H15N

InChI: InChI=1S/C21H35N2O15P3/c1-2-3-4-5-6-7-8-9-10-11-34-14-16-13-23(21(26)22-20(16)25)19-12-17(24)18(36-19)15-35-40(30,31)38-41(32,33)37-39(27,28)29/h1,13,17-19,24H,3-12,14-15H2,(H,30,31)(H,32,33)(H,22,25,26)(H2,27,28,29)/t17-,18+,19+/m0/s1

Description

These nucleotide bear alkyne linked to pyrimidine through long flexible linkers, and were previously designed in Michal Hocek group at IOCB (https://pubs.acs.org/doi/10.1021/acs.orglett.8b01533).  Undecynyl-dUTP has a hydrophobic tether.

References

  • Panattoni, A., Pohl, R., & Hocek, M. (2018). Flexible Alkyne-Linked Thymidine Phosphoramidites and Triphosphates for Chemical or Polymerase Synthesis and Fast Postsynthetic DNA Functionalization through Copper-Catalyzed Alkyne–Azide 1, 3-Dipolar Cycloaddition. Organic letters, 20(13), 3962-3965.

 

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